- No Gram Stain
- No pre-tests
- No follow-on tests
- One panel for both Gram Negative & Gram Positive bacteria
- One minute set-up
- Over 1350 species coverage
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Test gram negative and gram positive bacteria in the same test panel Rapidly and accurately identify over 2,900 species of aerobic and anaerobic Bacteria, Yeasts, and Fungi using the Biolog Gen III Identification Phenotypic technology. Biolog’s advanced phenotypic technology provides valuable information on the properties of strains, in addition to a species-level identification. Molecular methods such as 16s sequencing and MALDI-TOF provide no information about the properties of the strain. Biolog’s carbon source utilisation technology identifies environmental and pathogenic microorganisms by producing a characteristic pattern or “metabolic fingerprint” from discrete test reactions performed within a 96 well microplate. Culture suspensions are tested with a panel of pre-selected assays, then incubated, read and compared to our extensive databases. -
Test gram negative and gram positive bacteria in the same test panel Rapidly and accurately identify over 2,900 species of aerobic and anaerobic Bacteria, Yeasts, and Fungi using the Biolog Gen III Identification Phenotypic technology. Biolog’s advanced phenotypic technology provides valuable information on the properties of strains, in addition to a species-level identification. Molecular methods such as 16s sequencing and MALDI-TOF provide no information about the properties of the strain. Biolog’s carbon source utilisation technology identifies environmental and pathogenic microorganisms by producing a characteristic pattern or “metabolic fingerprint” from discrete test reactions performed within a 96 well microplate. Culture suspensions are tested with a panel of pre-selected assays, then incubated, read and compared to our extensive databases.- No Gram Stain
- No pre-tests
- No follow-on tests
- One panel for both Gram Negative & Gram Positive bacteria
- One minute set-up
- Over 1350 species coverage
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Phenotype MicroArrays for Microbial Cells Biolog's Phenotype MicroArray™ Technology enables researchers to characterise cells in up to 1,920 assays and evaluate cell changes under thousands of culture conditions and physiological states in a simple, rapid, efficient and cost-effective manner. By measuring a cell’s response to a genetic or environmental alteration, this integrated system of cellular assays, instrumentation, and bioinformatics software reveals invaluable information to speed insight and discovery and expedite scientific publication. Phenotype MicroArrays (PMs) have broad applicability for genotype-phenotype characterisation as well as for determining optimal conditions for cellular growth, sporulation and germination, production of secondary metabolites, or enzymatic activities in cell lines. Phenotype MicroArrays are a proven method of cellular screening that is extremely beneficial in a wide range of research applications:- Discovering effects of loss or gain of gene function.
- Measuring/documenting changes in cell metabolism over time or under different environmental conditions.
- Improvement and QC of phenotypic stability of cell lines.
- Improved efficacy in the production of compounds in biological fermentation processes.
- Evaluation of new drug/antibiotic candidates in toxicological profiling and mode of action studies.
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Analysing Mitochondria at Higher Resolution with MitoPlate™ Technology Analysing Mitochondria at higher resolution with Biolog Technology MitoPlates™ provide a powerful new research tool by allowing scientists to run preconfigured sets of 96 mitochondrial function assays in one experiment. Mitochondria can be interrogated and characterised in novel ways, looking at rates of substrate metabolism, sensitivity to drugs and other chemicals, and effects of mutations in mitochondria-related genes. Assay Principle Mitochondrial function is assayed by measuring the rates of electron flow into and through the electron transport chain from metabolic substrates that produce NAD(P)H or FADH2 such as L-malate, succinate, pyruvate, etc. Each substrate follows a different route, using different transporters to enter the mitochondria and different dehydrogenases to produce NAD(P)H or FADH2, The electrons travel from the beginning (complex 1 or 2) to the distal portion of the electron transport chain where a tetrazolium redox dye (MC) acts as a terminal electron acceptor that turns purple upon reduction. Additional MitoPlate assays probe the sensitivity of the mitochondria to a set of 22 diverse inhibitors. Investigate how mitochondria change with:- Cell differentiation
- Cancer & Aging
- Neurological disorders
- Metabolic disorders
- Immune cell activation
- Bacterial/viral infection
- Inborn genetic defects
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Phenotype MicroArrays for Mammalian Cells Using Biolog’s Phenotype MicroArray™ Technology, any type of cell can be characterised for metabolically related phenotypes in over 1,000 assays in a simple, rapid, and cost-effective manner. By measuring a cell’s metabolic activity, including responses to a genetic alteration or chemical stimuli, this integrated system of cellular assays, instrumentation, and bioinformatic software reveals unique and insightful information on metabolic pathway activities, and cellular sensitivity to nutrients, hormones, cytokines, anti-cancer agents, and ions. By measuring energy output of cells, the technology also provides new assays for understanding mitochondrial function and toxicity. Phenotype MicroArrays enable insight and discovery to expedite scientific publications. This is accomplished using 96 well microplates, pre-loaded with hundreds of KEGG pathway-matched metabolic substrates, and metabolic effectors. Phenotype MicroArrays are a proven method of cellular screening that is beneficial in a wide range of research applications:
- Genotype/phenotype studies
- Cell line characterisation and QC
- Cellular metabolism, metabolic disorders, nutrition
- Cell energetics growth and death
- Hormone effects on cells
- Metabolic reprogramming in cancer, Warburg effect, anti-cancer drug sensitivity
- Mitochondrial toxicology in chemical/drug screens
- Stem cells and differentiation
- Cell line and bio process development
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Space saver and adaptable system for individual applications The LUXOmatic V2 from LMB is a premium blood separator with motor driven plates, touch screen and integrated bar code scanner.- Sophisticated motor driven blood separator
- Two independent separation places in one device – Saves working space, time and provides best economic benefit
- High quality of separated blood products
- Heavy duty industrial scale separations
- Paediatric bags extraction possibility
- Ergonomic design
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Completely adaptable system for all applications The LUXOmatic from LMB is a premium blood separator for blood products of the highest quality. The dual press system allows for blood separation in two places at the same time.- Quick blood separation bags and high recovery of thrombocytes
- Precise treatment of all Top/Top and Top/Bottom processes
- CRYO application
- Thrombocytes from Buffy Coat and PRP
- Adaptive optical sensor system for best possible distinction between red cells, thrombocytes and plasma
- Precise and durable mechanical system
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Innovative, real-time, Peer Comparison Software from Technopath Manufacturing Ltd. The web based system facilitates laboratories testing the same lot number of control material to access valuable information from their colleagues through peer comparison. The reports that are generated in IAMQC Peer compare the accuracy and precision of analytical processes between laboratories and peer groups. This information can be extremely valuable, indicating the user’s performance relative to their peer group and also providing powerful troubleshooting tools when attempting to resolve potential problems. To participate in IAMQC Peer, each individual laboratory submits their individual results or summary statistics (mean, standard deviation, and number of data points) to the central database maintained by Technopath Manufacturing Ltd. Laboratories data may be submitted manually on-line or, alternatively, captured by one of our many interfacing options. The information provided by IAMQC Peer can be used on a monthly basis to evaluate how well lab’s methods are operating, relative to the overall peer group. Users can also look at this peer data in real-time, interactive, tables online, when they are investigating a potential problem with accuracy or precision for an individual method. -
Select QC Rules and make meaningful QC decisions IAMQC Expert, from Technopath Manufacturing Ltd, is an interactive system that helps front line laboratory staff select QC rules, reduce unnecessary repeats and make meaningful QC decisions. IAMQC Expert allows the end-user to monitor method performance relative to clinical requirements and focus on the tests that require their attention. Times and technologies are changing rapidly. Instruments and methodologies are more accurate, precise and stable than they were a decade ago. Most laboratories have adopted these new technical advances, but few have modified their QC processes to match. Many laboratories are still using a 1-2s rule as recommended by Levey and Jennings in 1951. Technopath Manufacturing Ltd have designed a QC system that will alert users to significant changes and not generate QC flags when the system is operating safely within acceptable limits. The system compares method performance to defined quality requirements (rather than to last month’s data) and recommends QC strategies that will warn users when QC data points exceed acceptable performance - with a minimal number of false flags. In the design of our QC system we “balance” the quality control system to meet the changing performance and stability of the analytical system. -
Internal Quality Control Software from Technopath Manufacturing Ltd. IAMQC Daily is a comprehensive Internal Quality Control software that applies Westgard and/or any user-defined QC rules to individual QC results. The software automatically builds interactive Levey-Jennings charts and tables and provides summary and detailed customised reports to the end user. IAMQC Daily integrates with Microsoft Excel to produce customised electronic reports. The system also allows the import of pre-defined templates, resulting in instant system setups. Users can create audit trails, action logs and summary reports at the click of a button. IAMQC Daily comprises a centralised program that facilitates the analysis of multiple QC materials, across numerous departments in a laboratory setting. The system can also be integrated with IAMQC Peer to satisfy both Internal and External QC requirements. IAMQC Daily offers a centralised review of all QC data from all laboratories/instruments. Central administrator access facilitates managers to review QC performance at multiple facilities – no need to visit each laboratory site. Closer monitoring of QC from remote locations without additional costs provides a flexible option for managing the inter and intra-lab performance. The software works on an ‘open’ platform that allows the end user to add all types of control material from a range of laboratories. Both IAMQC Daily and Expert can run using an internet OR intranet connection. Each PC license allows the user to manage an unlimited number of departments, control materials (not limited to Technopath materials) and instruments. An unlimited number of user logins can be added to the system at any stage. An administrator module can also manage user logins, customising the functionality that is available to each user. All data can also be filtered using the same logic to apply a user-friendly atmosphere and save time scrolling through data. -
Microbial-coated test surfaces for evaluating surface sampling competency Qualification of personnel who collect surface samples is a regulatory requirement and a crucial activity for an effective environmental monitoring program. Personnel sampling performance, including percent recovery, consistency, and aseptic technique, drives the quality of data that is generated and significantly impacts the integrity of an environmental monitoring program. Introducing Enverify™, the industry standard for evaluating surface sampling competency. Enverify™ Test Surfaces, from Stratix Labs, are the first standardised tool that enables you to evaluate and document surface sampling competency with quantitative data. Each Enverify™ Test Surface contains a precise quantity of microorganisms, providing a benchmark for you to evaluate, verify, and compare performance. Enverify™ is designed for use with contact plates and swab sampling tools. -
Hands-on training & performance verification improves pathogen detection. Data collected from environmental sampling of surfaces is highly dependent on the operator. Understanding and quantitatively characterising the percent recovery and consistency of sample collection by an operator drives improved detection and prevention of pathogens. Performance verification involves determining the percent recovery and consistency of an operator who collects samples in an environmental sampling program. Introducing Enverify™, a quantitative positive control for environmental sampling programs and comprises a flat substrate with a specific quantity of viable microorganisms coated on the surface. The microbes are safe-to-handle and are coated across a 10 cm x 10 cm area. Enverify™ provides a standardised tool for hands-on training and performance verification of operators that collect samples in environmental sampling programs. Enverify™ is compatible with contact plates, swab sampling devices, and sponge sample devices. Activities Involving Environmental Sampling:- Environmental monitoring for pathogens or indicator organisms
- Sanitation verification using ATP or indicator organisms
- Verification of hygienic restoration following adverse events
- Verification of containment during construction activities