Clinical Diagnostic Quality Solutions for SARS-CoV-2 Variant Analysis
AccuPlex SARS-CoV-2 Variant Panel 1 contains the full SARS-CoV-2 genomic RNA with a focus on S-gene mutations (Table 1) in three prominent variants of concern (VOC): UK variant B.1.1.7, South Africa variant B.1.351, and Brazil variant P.1. The kit has one vial for each variant as well as a fourth wild type (reference sequence NC_045512) control vial. An RNase P negative control vial is also included.
Product Details
All panels are for Research Use Only. Not for use in diagnostic procedures.
| AccuPlex SARS-CoV-2 Variant Panel 1 | |||
|---|---|---|---|
| Material Number | Strain | Pack Size | Concentration |
| 0505-0241 | UK B.1.1.7 | Positive 4 x 1.5 mL Negative 1 x 1.5 mL |
Positive 15,000 cp/mL Negative 5000 cp/mL |
| S. Africa B.1.351 | |||
| Brazil P.1 | |||
| Wuhan Wild Type | |||
| RNase P negative | |||
Mutations and Variant Strains
Table 1: Mutations and variant strains contained in the AccuPlex SARS-CoV-2 Variant Panel 1
| Amino Acid Change | Nucleotide Change | B.1.1.7 UK variant | B.1.351 S. Africa variant | P.1 Japan/Brazil variant |
|---|---|---|---|---|
| L18F | C21614T | X | ||
| T20N | C21621A | X | ||
| P26S | C21638T | X | ||
| HV 69-70 deletion | 21765-21770 deletion | X | ||
| D80A | A21801C | X | ||
| D138Y | G21974T | X | ||
| Y144 deletion | 21991-21993 deletion | X | ||
| R190S | G22132T | X | ||
| D215G | A22206G | X | ||
| 242_244 DelLAL | 22286-22294 Del | X | ||
| K417N | G22813T | X | ||
| K417T | A22812C | X | ||
| E484K | G23012A | X | X | |
| N501Y | A23063T | X | X | X |
| A570D | C23271A | X | ||
| D614G | A23403G | X | X | X |
| H655Y | C23525T | X | ||
| P681H | C23604A | X | ||
| A701V | C23664T | X | ||
| T716I | C23709T | X | ||
| S982A | T24506G | X | ||
| T1027I | C24642T | X | ||
| D1118H | G24914C | X | ||
| V1176F | G25088T | X |
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