Drug Discovery with Biolog Technologies
BiOLOG’s Phenotype MicroArray™ Technology for Microbial and Mammalian Cells, and new MitoPlate™ assays are used by pharmaceutical companies, biotech’s and academic institutions to assist with new drug target identification and drug re-purposing, and any applications in the process of developing solutions for the treatment and curing of disease.
Benefits of Phenotype MicroArrays in Drug Discovery:
Complement DNA microarrays. DNA microarrays allow scientists to measure the expression of thousands of genes of a cell under one growth condition, whereas Phenotype MicroArrays allow scientists to measure the effect of one gene in the cell under thousands of growth conditions.
Provide rapid answers to critical questions about cellular properties in a simple, rapid, efficient, and cost- effective process.
Provide rapid answers to how a gene of unknown function affects a cell at a physiological level.
Provide cell-to-cell comparisons to find novel drug targets based on in vivo physiological differences.
Provide a means to assay the effect of a drug on thousands of cellular targets under thousands of physiological states of the cell.
Provide rapid answers to questions about how a new lead affects a cell at a biochemical level.
Provide information on how new drug leads compare to and interact with existing drugs.
Reduce the time and cost of slow and cumbersome animal, plant, or human studies in late development.
Eliminate unproductive leads and projects, saving substantial R&D budget dollars that would be wasted in later development.
