Phenotype MicroArrays for Mammalian Cells
Using Biolog’s Phenotype MicroArray™ Technology, any type of cell can be characterised for metabolically related phenotypes in over
1,000 assays in a simple, rapid, and cost-effective manner.
By measuring a cell’s metabolic activity, including responses to a genetic alteration or chemical stimuli, this
integrated system of cellular assays, instrumentation, and bioinformatic software reveals unique and insightful information on metabolic pathway activities, and cellular sensitivity to nutrients, hormones, cytokines, anti-cancer agents, and ions. By measuring energy output of cells, the technology also provides new assays for understanding mitochondrial function and toxicity. Phenotype MicroArrays enable insight and discovery to expedite scientific publications.
This is accomplished using 96 well microplates, pre-loaded with hundreds of KEGG pathway-matched metabolic substrates, and metabolic effectors.
Phenotype MicroArrays are a proven method of cellular screening that is beneficial in a wide range of research applications:
Genotype/phenotype studies
Cell line characterisation and QC
Cellular metabolism, metabolic disorders, nutrition
Cell energetics growth and death
Hormone effects on cells
Metabolic reprogramming in cancer, Warburg effect, anti-cancer drug sensitivity
Mitochondrial toxicology in chemical/drug screens
Stem cells and differentiation
Cell line and bio process development