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EcoPlates™ Examine environmental community diversity with Biolog EcoPlates™. Biolog EcoPlates provide a sensitive and reliable index of environmental change. This approach, called community-level physiological profiling (CLPP), is effective at distinguishing spatial and temporal changes in the metabolism of microbial communities. Microbial communities provide useful information about environmental change. Microorganisms are present in virtually all environments and are typically the first organisms to react to chemical and physical changes in the environment. Changes in microbial communities are often a precursor to changes in the health and viability of the environment as a whole. -
Analysing Mitochondria at Higher Resolution with MitoPlate™ Technology Analysing Mitochondria at higher resolution with Biolog Technology MitoPlates™ provide a powerful new research tool by allowing scientists to run preconfigured sets of 96 mitochondrial function assays in one experiment. Mitochondria can be interrogated and characterised in novel ways, looking at rates of substrate metabolism, sensitivity to drugs and other chemicals, and effects of mutations in mitochondria-related genes. Assay Principle Mitochondrial function is assayed by measuring the rates of electron flow into and through the electron transport chain from metabolic substrates that produce NAD(P)H or FADH2 such as L-malate, succinate, pyruvate, etc. Each substrate follows a different route, using different transporters to enter the mitochondria and different dehydrogenases to produce NAD(P)H or FADH2, The electrons travel from the beginning (complex 1 or 2) to the distal portion of the electron transport chain where a tetrazolium redox dye (MC) acts as a terminal electron acceptor that turns purple upon reduction. Additional MitoPlate assays probe the sensitivity of the mitochondria to a set of 22 diverse inhibitors. Investigate how mitochondria change with:- Cell differentiation
- Cancer & Aging
- Neurological disorders
- Metabolic disorders
- Immune cell activation
- Bacterial/viral infection
- Inborn genetic defects
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Phenotype MicroArrays for Mammalian Cells Using Biolog’s Phenotype MicroArray™ Technology, any type of cell can be characterised for metabolically related phenotypes in over 1,000 assays in a simple, rapid, and cost-effective manner. By measuring a cell’s metabolic activity, including responses to a genetic alteration or chemical stimuli, this integrated system of cellular assays, instrumentation, and bioinformatic software reveals unique and insightful information on metabolic pathway activities, and cellular sensitivity to nutrients, hormones, cytokines, anti-cancer agents, and ions. By measuring energy output of cells, the technology also provides new assays for understanding mitochondrial function and toxicity. Phenotype MicroArrays enable insight and discovery to expedite scientific publications. This is accomplished using 96 well microplates, pre-loaded with hundreds of KEGG pathway-matched metabolic substrates, and metabolic effectors. Phenotype MicroArrays are a proven method of cellular screening that is beneficial in a wide range of research applications:- Genotype/phenotype studies
- Cell line characterisation and QC
- Cellular metabolism, metabolic disorders, nutrition
- Cell energetics growth and death
- Hormone effects on cells
- Metabolic reprogramming in cancer, Warburg effect, anti-cancer drug sensitivity
- Mitochondrial toxicology in chemical/drug screens
- Stem cells and differentiation
- Cell line and bio process development
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Microbial ID microplates from Biolog Biolog Solutions for Microbial Identification Rapidly and accurately identify nearly 3,000 species of aerobic and anaerobic bacteria, yeast, and fungi. In addition to species-level identification, Biolog’s advanced phenotypic technology provides valuable information on the functional properties of strains. Biolog’s carbon source utilisation technology identifies environmental and pathogenic microorganisms by producing a characteristic pattern or “metabolic fingerprint” from discrete test reactions performed within a 96-well microplate. Culture suspensions are tested with a panel of pre-selected assays, then incubated, read and compared to our extensive database. Biolog’s Microbial ID microplates incorporate a patented redox tetrazolium dye that changes colour as a result of cellular respiration, providing a metabolic fingerprint. Our complete solution includes instruments, consumables, databases, software. -
Provides A Superior Tracheal Seal … A Better Fit and Better Seal The MICROCUFF* tube from AVANOS, has advanced microthin polyurethane cuff material that allows the channels to “self-seal,” reducing the possibility of leakage. The build of the tube provides an effective seal at low cuff pressure. In turn, the MICROCUFF* may reduce micro-aspiration of potentially infectious pharyngeal secretions14. What’s more, it is designed for better contact with tracheal contour14. The thinner material enables greater visualisation of vocal cords when cuff is deflated. The MICROCUFF* is non-sterile and made from natural rubber that is latex-free. Intended for use in adults and for single-use. REFS: For references please refer to attached brochure - View MICROCUFF* Endotracheal Tubes Brochure here -
Proven to provide an 89% cleaner catheter tip7 BALLARD* Turbo-Cleaning Closed Suction System from AVANOS, which features technology from BALLARD* trach care, is the only catheter that retracts within a unique and isolated turbulent cleaning chamber. The turbulent cleansing action results in an 89% cleaner catheter tip compared to a standard closed suction system7. This reduced colonisation may help reduce risk of VAE and VAP in your ventilated patients. Manipulation of the ventilator circuit can increase cross-contamination – a leading cause of VAP.7 To help protect patients, a closed ventilator circuit is recognised as a best practice in the prevention of VAP3,5 to maintain ventilation and oxygen therapy throughout suctioning, preventing approximately 50% of the lung volume fall observed when suctioning after disconnection from the ventilator.4 Closed suctioning is a best practice that protects patients and caregivers.3,5 REFS: For references please refer to attached brochure - View Closed Suction Systems Brochure here -
A new standard for paediatric airway management MICROCUFF* Paediatric Endotracheal Tubes from AVANOS, designed specifically for the paediatric anatomy, offer the advantages of a cuffed tube, reducing tracheal trauma and providing a sealed airway that allows minimal and low flow anaesthesia use.1 Its short and cylindrical cuff membrane compensates for different sized and shaped paediatric airways, reducing the need for replacing oversized tracheal tubes, and resulting in lower re-intubation rates.13 The MICROCUFF* brand has changed the existing green Vent Connector on all of the MICROCUFF* tubes and replaced it with a blue Vent Connector. REFS: For references please refer to attached brochure - View MICROCUFF* Endotracheal Tubes Brochure here -
Provides A Superior Tracheal Seal … Proven to Reduce Leakage AVANOS* MICROCUFF* Subglottic Suctioning Adult Endotracheal Tubes are available in adult sizes with a Murphy Eye. They include a separate lumen with a dorsal opening above the cuff to provide access to the subglottic space. The subglottic space is reached via a normally open suction valve which includes a one-way port for rinsing the subglottic space with sterile saline (0.95% Sodium Chloride solution) or administering an air bolus to assist in maintaining suction lumen patency. Multiple size options available for the MICROCUFF* Subglottic Suctioning Adult Endotracheal Tube. Sizing options for the inner diameter vary between 7mm and 9mm. Similarly, the outer diameter sizing ranges from 10.4mm to 12.8mm. Cuff sizes come in 28mm and 30mm. The MICROCUFF* Subglottic Suctioning Adult Endotracheal Tubes are manufactured from natural rubber that is latex-free. EO Sterilised, they should be used no more than once. REFS: For references please refer to attached brochure - View MICROCUFF* Endotracheal Tubes Brochure here -
Multiple access. Multiple procedures. One closed circuit. The BALLARD* Multi-Access Port Closed Suction System from AVANOS, features a compact rotating manifold that provides multiple ports to access the patient’s airway, without jeopardising integrity of the closed circuit. A closed circuit helps you protect your patient from cross-contamination, VAE and VAP3. Also available: BALLARD* Mini-BAL Sampling Catheter Designed for use with the BALLARD* Multi-Access Port System, insert the BALLARD* Mini-BAL Sampling Catheter through the alternate therapy port to obtain a lower respiratory tract sample without opening the ventilator circuit. REFS: For references please refer to attached brochure - View Closed Suction Systems Brochure here -
BALLARD* Mini-BAL Sampling Catheter Proven to enable a more accurate diagnosis for more targeted antibiotic treatment. The AVANOS BALLARD* Mini-BAL Sampling Catheter is a telescoping catheter that safely samples a patient’s lower respiratory tract secretions, giving physicians the data they need to make an accurate lung infection diagnosis and prescribe targeted antibiotic treatment.6 Using bronchoalveolar lavage as a tool to help diagnose lower respiratory tract disease has been shown to reduce both antibiotic usage and healthcare costs.2 The BALLARD* Mini-BAL Sampling Catheter has a soft, directional tip that allows safe and quick retrieval of lower respiratory tract samples. This can help avoid the false negatives and false positives seen in an estimated 23% of endotracheal aspirate cultures.2 These secretions from the distal airway can help identify infectious pathogens of the lung for a microbiologically confirmed diagnosis. Helpful features of the tool includes a suction tube adapter, directional oxygen port, atraumatic tip, and suction tube adapter. Clinicians have multiple models available to them, varying in the size of the outer EVA catheter and inner PVC catheter. The Mini-BAL Sampling Catheter comes EO sterilised in 13fr or 16fr. Designed for use with the AVANOS* Multi-Access Port System. REFS: For references please refer to attached brochure - View Sampling Catheter Brochure here -
ENFit Bottle Adaptors ISOSAF Bottle adaptors for enteral and oral syringes. Available in five sizes to fit the majority of medicine bottles. -
ENFit Adaptors from Enteral UK ENFit To Funnel Adaptor Transition Adapter for ENFit Syringe to Funnel Tube. With tethered cap. Funnel to ENFit Adaptor Transition Adapter for Non ENFit Funnel Syringe to ENFit Tube. Y-Port Adaptor Double male ENFit connector (ISO 80369-3), converts any ENFit single port feeding tube to Y-Port, sterile. Medicine Bottle Adaptor Stepped Bottle Adaptor, 15-27mm, male ENFit connector (ISO 80369-3).
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