Biolog Solutions for Characterising Diversity
Phenotype MicroArray™ Technology from Biolog
Get relevant data you need faster with Phenotype MicroArrays. Phenotype MicroArrays enable researchers to quickly gain cellular insights, by growing cells in thousands of culture conditions simultaneously.
Phenotype MicroArray™ technology is a proven method of phenotypic cellular screening that is extremely beneficial in a wide range of research applications:
- Uncover functional effects of gene editing
- Measure changes in cell metabolism over time or under different environmental conditions
- Evaluate drug/antibiotic candidates in toxicological profiling and mode of action studies
- Monitor phenotypic drift and QC of cell line passages
- Optimise efficacy in bioprocessing production
When using Phenotype MicroArrays, you need an instrument that will read at the right wavelengths and measure the changes kinetically over time at short intervals. You also need a software package to help you analyse all that data and identify the differences between your samples. With the Odin™ platform you can characterise phenotypes by monitoring growth curves and cell metabolism kinetics for microbial or mammalian cells for up to 50 plates at the same time. When combined with Phenotype MicroArrays, Odin can analyse up to 4,800 conditions unattended for hours or days.
OPdin for Growth Kinetics
Odin sees what’s happening in two ways.
It measures a reporter dye at one wavelength to measure NADH production, effectively reporting the rate of metabolic respiration.
Odin also measures optical density (OD) at a second wavelength to determine how quickly the microbes are dividing. Taken together, you get a full picture of how your microbes grow best.
If you’re focused on cell growth, just leave the dye out. Odin automatically compares cell growth and metabolic activity curves to provide you with a clearer picture of how fast or slow your microbes are growing.
